|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
24
|
|
pubmed:dateCreated |
2008-11-25
|
|
pubmed:abstractText |
C4-Fluorinated analogues of solamin, an antitumor acetogenin, were synthesized and investigated for their antitumor activities against 39 tumor cell lines. C4-Fluorinated solamins showed more potent growth inhibitory activity against cancer cell lines than solamin.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1464-3405
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
15
|
|
pubmed:volume |
18
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
6451-3
|
|
pubmed:meshHeading |
pubmed-meshheading:18993063-Acetogenins,
pubmed-meshheading:18993063-Antineoplastic Agents,
pubmed-meshheading:18993063-Benzethonium,
pubmed-meshheading:18993063-Cell Line, Tumor,
pubmed-meshheading:18993063-Chemistry, Pharmaceutical,
pubmed-meshheading:18993063-Drug Design,
pubmed-meshheading:18993063-Drug Screening Assays, Antitumor,
pubmed-meshheading:18993063-Humans,
pubmed-meshheading:18993063-Inhibitory Concentration 50,
pubmed-meshheading:18993063-Models, Chemical,
pubmed-meshheading:18993063-Stereoisomerism,
pubmed-meshheading:18993063-Structure-Activity Relationship
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Synthesis of C4-fluorinated solamins and their growth inhibitory activity against human cancer cell lines.
|
|
pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
