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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2008-11-10
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pubmed:abstractText |
Bothropstoxin-II a calcium-dependent enzyme from Bothrops jararacussu venom causes tissue damage and several haemostatic disorders including platelet aggregation. In order to elucidate the structural determinants of its multiple pharmacological activities, we have studied the effects of suramin on Bothropstoxin-II and present details concerning the mode of binding.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0929-8665
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1002-8
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pubmed:meshHeading |
pubmed-meshheading:18991778-Algorithms,
pubmed-meshheading:18991778-Animals,
pubmed-meshheading:18991778-Binding Sites,
pubmed-meshheading:18991778-Bothrops,
pubmed-meshheading:18991778-Catalytic Domain,
pubmed-meshheading:18991778-Computer Simulation,
pubmed-meshheading:18991778-Creatine Kinase,
pubmed-meshheading:18991778-Crotalid Venoms,
pubmed-meshheading:18991778-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:18991778-Group II Phospholipases A2,
pubmed-meshheading:18991778-Mice,
pubmed-meshheading:18991778-Models, Molecular,
pubmed-meshheading:18991778-Protein Conformation,
pubmed-meshheading:18991778-Reptilian Proteins,
pubmed-meshheading:18991778-Scattering, Small Angle,
pubmed-meshheading:18991778-Suramin
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pubmed:year |
2008
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pubmed:articleTitle |
Biochemical and structural investigations of Bothropstoxin-II, a myotoxic Asp49 phospholipase A2 from Bothrops jararacussu venom.
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pubmed:affiliation |
Center for Structural Molecular Biology, Brazilian Synchrotron Light Laboratory, LNLS Campinas, SP, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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