rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-17
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pubmed:abstractText |
Currently, no agent has been confirmed as preventing the fibrosing progression of non-alcoholic steatohepatitis (NASH). In this study, rosiglitazone was used in the clinical treatment of insulin resistance in patients with type 2 diabetes mellitus. However, its protective effect on non-alcoholic fibrosing steatohepatitis is not clear. The study aimed to elucidate the effect and the mechanism of rosiglitazone in inhibiting nutrition-related fibrosis in mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1502-7708
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
358-65
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pubmed:meshHeading |
pubmed-meshheading:18991162-Alanine Transaminase,
pubmed-meshheading:18991162-Animals,
pubmed-meshheading:18991162-Aspartate Aminotransferases,
pubmed-meshheading:18991162-Blotting, Western,
pubmed-meshheading:18991162-Connective Tissue Growth Factor,
pubmed-meshheading:18991162-Fatty Liver,
pubmed-meshheading:18991162-Hepatic Stellate Cells,
pubmed-meshheading:18991162-Hypoglycemic Agents,
pubmed-meshheading:18991162-Immunoenzyme Techniques,
pubmed-meshheading:18991162-Liver Cirrhosis,
pubmed-meshheading:18991162-Liver Function Tests,
pubmed-meshheading:18991162-Male,
pubmed-meshheading:18991162-Mice,
pubmed-meshheading:18991162-Mice, Inbred C57BL,
pubmed-meshheading:18991162-PPAR gamma,
pubmed-meshheading:18991162-Thiazolidinediones,
pubmed-meshheading:18991162-Transforming Growth Factor beta1
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pubmed:year |
2009
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pubmed:articleTitle |
Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice.
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pubmed:affiliation |
Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, China. nanyuemin@163.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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