Linked Life Data

18989879

Source:http://linkedlifedata.com/resource/pubmed/id/18989879

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-1-15
pubmed:abstractText
Brain abscesses in children with leukemia or other malignancies are rare and potentially fatal. We report on four children who developed brain abscesses during treatment for acute lymphoblastic leukemia (ALL). All patients received multimodal broad-spectrum antibiotic therapy and liposomal amphotericin-B in combination with hyperbaric oxygen. First-line antimicrobial treatment was modified when a causative organism was isolated. All four patients survived, with two patients showing complete resolution of neurological and MRI abnormalities and with two patients still having residual lesions. To date, all patients are in remission with three patients still receiving antileukemic therapy. Brain abscesses can be successfully managed by a multimodality approach even in severely immunocompromised cancer patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1545-5017
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
408-11
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Management of brain abscesses in children treated for acute lymphoblastic leukemia.
pubmed:affiliation
Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology, Medical University of Graz, Graz, Austria. herwig.lackner@meduni-graz.at
pubmed:publicationType
Journal Article, Case Reports