Linked Life Data

18987402

Source:http://linkedlifedata.com/resource/pubmed/id/18987402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-11-6
pubmed:abstractText
Primary percutaneous coronary intervention (PCI) is an established reperfusion strategy in the treatment of acute myocardial infarction with ST-segment elevation (STEMI). Nevertheless, myocardial damage is not terminated immediately, even with successful primary PCI, which eliminates the epicardial occlusion. Despite the success of contemporary reperfusion therapy and effective restoration of epicardial coronary flow, many patients have suboptimal flow at the tissue level within the myocardium. Studies indicate that these patients have a decreased recovery of left ventricular function and poor long-term prognosis. This could be due to reperfusion injury, embolization of epicardial thrombus or plaque debris jeopardizing tissue-level perfusion. This article attempts to review the process of microvascular dysfunction following reperfusion of STEMI with primary PCI and different strategies tried thus far to improve this.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1557-2501
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
603-14
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Microvascular dysfunction following primary percutaneous coronary intervention in the setting of ST-elevation myocardial infarction.
pubmed:affiliation
University of Arizona College of Medicine, Tucson, AZ 85724, USA. drkutty2@gmail.com
pubmed:publicationType
Journal Article, Review