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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-1-18
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pubmed:abstractText |
The pathogenesis of nonalcoholic steatohepatitis (NASH) is still unclear. Recently, the 2-hit hypothesis was proposed, in which nitric oxide production, representing oxidative stress, was proposed as a very important candidate for the second hit.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1530-0277
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pubmed:author |
pubmed-author:FujitaKojiK,
pubmed-author:InamoriMasahikoM,
pubmed-author:IwasakiTomoyukiT,
pubmed-author:KirikoshiHiroyukiH,
pubmed-author:MaeyamaShiroS,
pubmed-author:NakajimaAtsushiA,
pubmed-author:NozakiYuichiY,
pubmed-author:SaitoSatoruS,
pubmed-author:TakahashiHirokazuH,
pubmed-author:TerauchiYasuoY,
pubmed-author:WadaKoichiroK,
pubmed-author:YonedaMasatoM
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pubmed:issnType |
Electronic
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pubmed:volume |
34 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S18-24
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pubmed:meshHeading |
pubmed-meshheading:18986378-Amino Acids,
pubmed-meshheading:18986378-Animals,
pubmed-meshheading:18986378-Blotting, Western,
pubmed-meshheading:18986378-Choline,
pubmed-meshheading:18986378-Choline Deficiency,
pubmed-meshheading:18986378-Diet,
pubmed-meshheading:18986378-Disease Models, Animal,
pubmed-meshheading:18986378-Fatty Liver,
pubmed-meshheading:18986378-Intra-Abdominal Fat,
pubmed-meshheading:18986378-Liver,
pubmed-meshheading:18986378-Male,
pubmed-meshheading:18986378-Nitrates,
pubmed-meshheading:18986378-Nitric Oxide,
pubmed-meshheading:18986378-Nitric Oxide Synthase Type II,
pubmed-meshheading:18986378-Nitrites,
pubmed-meshheading:18986378-Oxidative Stress,
pubmed-meshheading:18986378-RNA, Messenger,
pubmed-meshheading:18986378-Rats,
pubmed-meshheading:18986378-Rats, Inbred F344,
pubmed-meshheading:18986378-Tyrosine
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pubmed:year |
2010
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pubmed:articleTitle |
Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model.
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pubmed:affiliation |
From the Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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