rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2008-12-16
|
pubmed:abstractText |
Nevirapine is widely used in the developing world for the prevention of mother-to-child transmission (PMTCT) of HIV. A single mutation in the HIV genome is sufficient to lead to significant nevirapine resistance. Persistence of low-level drug concentrations in body compartments can foster resistance formation. In this study, concentration-time courses of nevirapine after single-dose administration were analysed over an extended post-partum period.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1460-2091
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
63
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
170-7
|
pubmed:meshHeading |
pubmed-meshheading:18974161-Adult,
pubmed-meshheading:18974161-Chromatography, Liquid,
pubmed-meshheading:18974161-Female,
pubmed-meshheading:18974161-HIV Infections,
pubmed-meshheading:18974161-Humans,
pubmed-meshheading:18974161-Infant, Newborn,
pubmed-meshheading:18974161-Infectious Disease Transmission, Vertical,
pubmed-meshheading:18974161-Male,
pubmed-meshheading:18974161-Milk, Human,
pubmed-meshheading:18974161-Mothers,
pubmed-meshheading:18974161-Nevirapine,
pubmed-meshheading:18974161-Plasma,
pubmed-meshheading:18974161-Pregnant Women,
pubmed-meshheading:18974161-Tandem Mass Spectrometry,
pubmed-meshheading:18974161-Uganda
|
pubmed:year |
2009
|
pubmed:articleTitle |
Persistence of nevirapine in breast milk and plasma of mothers and their children after single-dose administration.
|
pubmed:affiliation |
Institute of Tropical Medicine and International Health, Charité-University Medicine Berlin, Berlin, Germany. andrea-ursula.kunz@charite.de
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|