Linked Life Data

18959427

Source:http://linkedlifedata.com/resource/pubmed/id/18959427

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
2008-11-14
pubmed:abstractText
alpha-Hydroxypropargylsilanes undergo rearrangement to form reactive lithium allenolates. The resulting alpha-acylvinyl anion equivalents undergo highly selective additions to N-tert-butanesulfinyl imines generating beta-substituted aza-MBH-type products. High yields are achieved for a wide range of alpha-hydroxypropargylsilanes as well as for a diverse selection of imines. The reactions proceed with good to excellent diastereoselectivity and regioselectivity (8-20:1 major/ Sigma minor) favoring the Z-isomer of the alkene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1523-7052
pubmed:author
pubmed:issnType
Electronic
pubmed:day
20
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5227-30
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Highly selective alpha-acylvinyl anion additions to imines.
pubmed:affiliation
Department of Chemistry, Northwestern University, Evanston, Illinois 60208, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't