rdf:type |
|
lifeskim:mentions |
umls-concept:C0016904,
umls-concept:C0019564,
umls-concept:C0027882,
umls-concept:C0231491,
umls-concept:C0439810,
umls-concept:C0871261,
umls-concept:C1280500,
umls-concept:C1444748,
umls-concept:C1519355,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
4
|
pubmed:dateCreated |
1991-10-24
|
pubmed:abstractText |
Influence of 4-E-BPE on the amplitude of population spices (PS) evoked in CA1 area by Shaffer collateral stimulation in hippocampal slices were analysed. Bath application of 4-E-BPE (10(-6)-10(-5) M) led to a pronounced increase in the amplitude of the PS, the appearance of secondary PS and then introduction of GABA led to restoring original state. The 4-E-BPE was more potent than picrotoxin. These findings suggest that 4-E-BPE suppress inhibitory synaptic transmission in the CA1 region of hippocampus.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0365-9615
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
111
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
339-41
|
pubmed:dateRevised |
2008-10-8
|
pubmed:meshHeading |
pubmed-meshheading:1893124-Animals,
pubmed-meshheading:1893124-Bicyclo Compounds,
pubmed-meshheading:1893124-Bicyclo Compounds, Heterocyclic,
pubmed-meshheading:1893124-Evoked Potentials,
pubmed-meshheading:1893124-GABA Antagonists,
pubmed-meshheading:1893124-Hippocampus,
pubmed-meshheading:1893124-Mice,
pubmed-meshheading:1893124-Mice, Inbred BALB C,
pubmed-meshheading:1893124-Neurons,
pubmed-meshheading:1893124-Organophosphorus Compounds,
pubmed-meshheading:1893124-Picrotoxin,
pubmed-meshheading:1893124-Synapses
|
pubmed:year |
1991
|
pubmed:articleTitle |
[Effects of gamma-aminobutyric acid antagonist, 4-ethyl bicyclo-phosphate, on total and synaptic evoked responses in neurons of hippocampal slices].
|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro,
English Abstract
|