| pubmed-article:18930441 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C0026969 | lld:lifeskim |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C0011303 | lld:lifeskim |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C1155046 | lld:lifeskim |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C0178499 | lld:lifeskim |
| pubmed-article:18930441 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:18930441 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18930441 | pubmed:dateCreated | 2008-11-10 | lld:pubmed |
| pubmed-article:18930441 | pubmed:abstractText | A dynamic equilibrium between proliferation and programmed cell death (PCD) of auto-reactive T lymphocytes plays a pivotal role in the prevention of autoimmune diseases. We analyzed T lymphocytes myelin basic protein (MBP)-specific PCD and proliferation in demyelinating diseases. Results showed that MBP-specific PCD was significantly decreased in CD4+ and CD8+ T lymphocytes of progressive multifocal leukoencephalopathy (PML), not determined leukoencephalopathy (NDLE), and acute MS (AMS) patients compared to patients with stable MS (SMS) and healthy controls. MBP-specific proliferation/PCD rates were high in CD4+ T lymphocytes of PML, NDLE, and AMS patients, and in CD8+ T cells of PML and AMS individuals alone. Alterations of the balance between MBP-specific proliferation and PCD are present in demyelinating diseases and could play a major role in the pathogenesis of these diseases. | lld:pubmed |
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| pubmed-article:18930441 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18930441 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18930441 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18930441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:18930441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18930441 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18930441 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:18930441 | pubmed:issn | 1521-7035 | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:ClericiMarioM | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:LonghiRenatoR | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:DelbueSerenaS | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:MaseratiRenat... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:FerrantePasqu... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:SaresellaMari... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:MarchioniEnri... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:GueriniFranca... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:MarventanoIva... | lld:pubmed |
| pubmed-article:18930441 | pubmed:author | pubmed-author:ZanzotteraMil... | lld:pubmed |
| pubmed-article:18930441 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18930441 | pubmed:volume | 129 | lld:pubmed |
| pubmed-article:18930441 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18930441 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18930441 | pubmed:pagination | 509-17 | lld:pubmed |
| pubmed-article:18930441 | pubmed:dateRevised | 2011-10-6 | lld:pubmed |
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| pubmed-article:18930441 | pubmed:meshHeading | pubmed-meshheading:18930441... | lld:pubmed |
| pubmed-article:18930441 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18930441 | pubmed:articleTitle | Myelin basic protein-specific T lymphocytes proliferation and programmed cell death in demyelinating diseases. | lld:pubmed |
| pubmed-article:18930441 | pubmed:affiliation | Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS, IRCCS S. Maria Nascente, Via Capecelatro 66, 20148, Milan, Italy. | lld:pubmed |
| pubmed-article:18930441 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18930441 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:18930441 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18930441 | lld:pubmed |
