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pubmed-article:18927449pubmed:abstractTextNotch signaling activity regulates arteriogenesis. Presenilin 1 (PS1) mediates Notch signaling activity via cleavage of Notch, liberating Notch intracellular domain (NICD). We tested the hypothesis that simvastatin enhances arteriogenesis after stroke by increasing PS1 activation of the Notch signaling pathway.lld:pubmed
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pubmed-article:18927449pubmed:articleTitleSimvastatin increases notch signaling activity and promotes arteriogenesis after stroke.lld:pubmed
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