Source:http://linkedlifedata.com/resource/pubmed/id/18922422
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2008-10-16
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pubmed:abstractText |
Recombinant activated factor VII (rFVIIa) is increasingly being given to treat massive bleeding. However, there is no clear guidance on which patients are suitable for treatment and how the effects of treatment should be monitored. The aim of this in vitro study was to assess the coagulation status of severely hemodiluted blood samples before and after treatment with therapeutic doses of rFVIIa and/or fibrinogen with 2 viscoelastic point-of-care coagulation analyzers: ROTEM (Pentapharm GmbH, Munich, Germany) and Sonoclot (Sienco Inc, Arvada, CO).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1532-8422
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
675-80
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pubmed:meshHeading |
pubmed-meshheading:18922422-Adult,
pubmed-meshheading:18922422-Blood Coagulation Tests,
pubmed-meshheading:18922422-Factor VIIa,
pubmed-meshheading:18922422-Fibrinogen,
pubmed-meshheading:18922422-Hemodilution,
pubmed-meshheading:18922422-Humans,
pubmed-meshheading:18922422-Male,
pubmed-meshheading:18922422-Point-of-Care Systems,
pubmed-meshheading:18922422-Recombinant Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Monitoring recombinant factor VIIa treatment: efficacy depends on high levels of fibrinogen in a model of severe dilutional coagulopathy.
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pubmed:affiliation |
Institute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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