rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2008-10-15
|
pubmed:abstractText |
Hepatoma cells are morphologically different from those of the normal liver. Intermediate filaments (IFs) are important in building the cellular architecture and maintaining the outline of cells. Plectin is a cross-linking protein that organizes the cytoskeleton into a stable meshwork, which can maintain the uniform size and shape of hepatocytes. Apoptosis might be the most possible pathway for creating plectin deficiency in the in vivo state.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0258-851X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
543-8
|
pubmed:meshHeading |
pubmed-meshheading:18853744-Apoptosis,
pubmed-meshheading:18853744-Blotting, Western,
pubmed-meshheading:18853744-Fluorescent Antibody Technique,
pubmed-meshheading:18853744-Humans,
pubmed-meshheading:18853744-Keratin-18,
pubmed-meshheading:18853744-Liver,
pubmed-meshheading:18853744-Plectin,
pubmed-meshheading:18853744-Staurosporine,
pubmed-meshheading:18853744-Tumor Cells, Cultured
|
pubmed:articleTitle |
Degradation of plectin with modulation of cytokeratin 18 in human liver cells during staurosporine-induced apoptosis.
|
pubmed:affiliation |
Department of Pathology, Jen Ai Hospital, Taichung, Taiwan, R.O.C.
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pubmed:publicationType |
Journal Article
|