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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-10-13
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pubmed:abstractText |
Inhalational anesthetics can cause profound hemodynamic effects including decreases in systemic vascular resistance and cardiac inotropy. Although widely used in uncontrolled hemorrhagic shock (UHS), their consequences compared with other anesthetic regimens are not well-studied. Ketamine-based total intravenous anesthesia (TIVA) may produce less profound cardiovascular depression, and has been used during elective surgery but rarely during traumatic shock. The purpose of this study was to compare the effects of isoflurane (ISO) and TIVA regimens in a swine grade V liver injury model. We hypothesized that TIVA would result in less hypotension and dysfunctional inflammation than ISO.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Dissociative,
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Inhalation,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Isoflurane,
http://linkedlifedata.com/resource/pubmed/chemical/Ketamine,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1529-8809
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
901-8; discussion 908-9
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pubmed:meshHeading |
pubmed-meshheading:18849809-Anesthesia, Intravenous,
pubmed-meshheading:18849809-Anesthetics, Dissociative,
pubmed-meshheading:18849809-Anesthetics, Inhalation,
pubmed-meshheading:18849809-Animals,
pubmed-meshheading:18849809-Cytokines,
pubmed-meshheading:18849809-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:18849809-Female,
pubmed-meshheading:18849809-Hemodynamics,
pubmed-meshheading:18849809-Inflammation Mediators,
pubmed-meshheading:18849809-Infusions, Intravenous,
pubmed-meshheading:18849809-Interleukin-6,
pubmed-meshheading:18849809-Interleukin-8,
pubmed-meshheading:18849809-Isoflurane,
pubmed-meshheading:18849809-Ketamine,
pubmed-meshheading:18849809-Oxygen Consumption,
pubmed-meshheading:18849809-Random Allocation,
pubmed-meshheading:18849809-Sensitivity and Specificity,
pubmed-meshheading:18849809-Shock, Hemorrhagic,
pubmed-meshheading:18849809-Swine,
pubmed-meshheading:18849809-Tumor Necrosis Factor-alpha
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pubmed:year |
2008
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pubmed:articleTitle |
Ketamine-based total intravenous anesthesia versus isoflurane anesthesia in a swine model of hemorrhagic shock.
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pubmed:affiliation |
Section of Trauma and Surgical Critical Care, Department of Surgery, Oregon Health & Science University, Portland, Oregon 97239, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
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