Source:http://linkedlifedata.com/resource/pubmed/id/18838388
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2008-11-12
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pubmed:abstractText |
IL-1 has a central role mediating inflammation and joint destruction in RA. Single nucleotide polymorphisms (SNPs) and haplotype structure in the promoter region can modulate IL-1 function. This study examined the effects of four common promoter SNPs in the IL-1 region on susceptibility and clinical characteristics of RA in British Caucasian patients and assessed the risk of RA by meta-analysis of published studies.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1462-0332
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1768-70
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pubmed:dateRevised |
2011-7-1
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pubmed:meshHeading |
pubmed-meshheading:18838388-Arthritis, Rheumatoid,
pubmed-meshheading:18838388-Case-Control Studies,
pubmed-meshheading:18838388-Disease Progression,
pubmed-meshheading:18838388-Female,
pubmed-meshheading:18838388-Genetic Predisposition to Disease,
pubmed-meshheading:18838388-Genotype,
pubmed-meshheading:18838388-Humans,
pubmed-meshheading:18838388-Interleukin-1beta,
pubmed-meshheading:18838388-Male,
pubmed-meshheading:18838388-Middle Aged,
pubmed-meshheading:18838388-Polymorphism, Single Nucleotide,
pubmed-meshheading:18838388-Promoter Regions, Genetic
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pubmed:year |
2008
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pubmed:articleTitle |
Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis.
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pubmed:affiliation |
Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road, Oxford OX3 7LD, UK. pille.harrison@ndos.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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