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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
2008-10-2
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pubmed:abstractText |
Evidence has accumulated in recent years suggestive of a genetic basis for a susceptibility to the development of radiation injury after cancer radiotherapy. The purpose of this study was to assess whether patients with severe radiation-induced sequelae (RIS; i.e., National Cancer Institute/CTCv3.0 grade, > or =3) display both a low capacity of radiation-induced CD8 lymphocyte apoptosis (RILA) in vitro and possess certain single nucleotide polymorphisms (SNP) located in candidate genes associated with the response of cells to radiation.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-10524426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-11173153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-11354248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-11483345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-11849780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-12965273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-14643949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-14652276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-15088388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-15328527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-15878096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-15880407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-15961779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-16182590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-16243816,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-16467085,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-16751059,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-16929324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-17003501,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-17076557,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-17395038,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-17497308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-7713792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-8989370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-9226332,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18829510-9853138
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AtencioDavid PDP,
pubmed-author:CoatJ PJP,
pubmed-author:CromptonNigel E ANE,
pubmed-author:DuboisJean-BernardJB,
pubmed-author:KramarAndrewA,
pubmed-author:MirimanoffRené-OlivierRO,
pubmed-author:MornexFrançoiseF,
pubmed-author:OzsahinMahmutM,
pubmed-author:PèlegrinAndréA,
pubmed-author:PetersSheilaS,
pubmed-author:RosensteinBarry SBS
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6284-8
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pubmed:dateRevised |
2010-9-21
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pubmed:meshHeading |
pubmed-meshheading:18829510-Apoptosis,
pubmed-meshheading:18829510-CD8-Positive T-Lymphocytes,
pubmed-meshheading:18829510-Case-Control Studies,
pubmed-meshheading:18829510-Fibrosis,
pubmed-meshheading:18829510-Genetic Predisposition to Disease,
pubmed-meshheading:18829510-Genotype,
pubmed-meshheading:18829510-Humans,
pubmed-meshheading:18829510-Neoplasms,
pubmed-meshheading:18829510-Polymorphism, Single Nucleotide,
pubmed-meshheading:18829510-Radiation Injuries,
pubmed-meshheading:18829510-Radiation Tolerance,
pubmed-meshheading:18829510-Radiotherapy,
pubmed-meshheading:18829510-Risk,
pubmed-meshheading:18829510-Time Factors,
pubmed-meshheading:18829510-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Single nucleotide polymorphisms, apoptosis, and the development of severe late adverse effects after radiotherapy.
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pubmed:affiliation |
INSERM U896, Institut de Recherche en Cancérologie de Montpellier, Department of Radiation Oncology, CRLC Val d'Aurelle-Paul Lamarque, Montpellier, France.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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