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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
2008-11-17
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|
pubmed:abstractText |
The aim of this study was to develop and validate a population pharmacokinetic model in order to describe ritonavir-boosted saquinavir concentrations dosed twice and once daily in human immunodeficiency virus (HIV)-infected patients from the UK, Uganda and Thailand and to identify factors that may influence saquinavir pharmacokinetics.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
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pubmed:issn |
1460-2091
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1344-55
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pubmed:meshHeading |
pubmed-meshheading:18824460-Adult,
pubmed-meshheading:18824460-Anti-HIV Agents,
pubmed-meshheading:18824460-Area Under Curve,
pubmed-meshheading:18824460-Female,
pubmed-meshheading:18824460-Great Britain,
pubmed-meshheading:18824460-HIV,
pubmed-meshheading:18824460-HIV Infections,
pubmed-meshheading:18824460-Humans,
pubmed-meshheading:18824460-Male,
pubmed-meshheading:18824460-Metabolic Clearance Rate,
pubmed-meshheading:18824460-Middle Aged,
pubmed-meshheading:18824460-Models, Theoretical,
pubmed-meshheading:18824460-Ritonavir,
pubmed-meshheading:18824460-Saquinavir,
pubmed-meshheading:18824460-Serum,
pubmed-meshheading:18824460-Thailand,
pubmed-meshheading:18824460-Uganda
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pubmed:year |
2008
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pubmed:articleTitle |
Population pharmacokinetics of ritonavir-boosted saquinavir regimens in HIV-infected individuals.
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pubmed:affiliation |
NIHR National Biomedical Research Centre, Royal Liverpool and Broadgreen University Hospital Trust, Liverpool, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Validation Studies
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