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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-12-1
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pubmed:abstractText |
Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conjectures regarding their possible involvement in the evolution of drug resistance. This work was aimed to identify selected microRNAs involved in the development of chemoresistance in ovarian cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1095-6859
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
111
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
478-86
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pubmed:meshHeading |
pubmed-meshheading:18823650-Antineoplastic Agents,
pubmed-meshheading:18823650-Blotting, Northern,
pubmed-meshheading:18823650-Blotting, Western,
pubmed-meshheading:18823650-Cell Line, Tumor,
pubmed-meshheading:18823650-Cisplatin,
pubmed-meshheading:18823650-Computational Biology,
pubmed-meshheading:18823650-Drug Resistance, Neoplasm,
pubmed-meshheading:18823650-Female,
pubmed-meshheading:18823650-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18823650-HeLa Cells,
pubmed-meshheading:18823650-Humans,
pubmed-meshheading:18823650-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:18823650-MicroRNAs,
pubmed-meshheading:18823650-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18823650-Ovarian Neoplasms,
pubmed-meshheading:18823650-Paclitaxel,
pubmed-meshheading:18823650-Polymerase Chain Reaction,
pubmed-meshheading:18823650-RNA, Messenger,
pubmed-meshheading:18823650-Up-Regulation
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pubmed:year |
2008
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pubmed:articleTitle |
Role of microRNAs in drug-resistant ovarian cancer cells.
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pubmed:affiliation |
Department of Hematology, Istituto Superiore di Sanità, Rome, Italy. antonio.sorrentino@iss.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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