Source:http://linkedlifedata.com/resource/pubmed/id/18817751
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-10-22
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pubmed:abstractText |
We demonstrate optical coherent control of the two-photon fluorescence of the blue fluorescent protein (BFP), which is of interest in investigations of protein-protein interactions. In addition to biological relevance, BFP represents an interesting target for coherent control from a chemical perspective due to its many components of highly nonexponential fluorescence decay and low quantum yield resulting from excited state isomerization. Using a genetic algorithm with a multiplicative (rather than ratiometric) fitness parameter, we are able to control the ratio of BFP fluorescence to second-harmonic generation without a considerable drop in the maximized signal. The importance of linear chirp and power-scaling on the discrimination process is investigated in detail.
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pubmed:grant | |
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-10087619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-10339561,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-11689940,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-11785758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-14623311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-14677136,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-15865396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-16852610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18817751-17721879
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1090-2104
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
376
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
733-7
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading | |
pubmed:year |
2008
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pubmed:articleTitle |
Control of the blue fluorescent protein with advanced evolutionary pulse shaping.
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pubmed:affiliation |
Center for Ultrafast Optical Science, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, MI 48109-2099, USA. etkaczyk@umich.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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