rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
In a recent report, we established at the genome-wide level those genes that are specifically upregulated in the endothelium of atherosclerotic plaques in human arteries. As the transcriptome data revealed that mRNA for the tetraspanin family member CD81 is significantly and specifically upregulated in the endothelium overlying early atheroma, we set out to validate these results on the protein level, and investigate the functional consequences of CD81 upregulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
1755-3245
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-96
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18805782-Antigens, CD,
pubmed-meshheading:18805782-Antigens, CD81,
pubmed-meshheading:18805782-Atherosclerosis,
pubmed-meshheading:18805782-Biological Markers,
pubmed-meshheading:18805782-Cell Adhesion,
pubmed-meshheading:18805782-Cells, Cultured,
pubmed-meshheading:18805782-Endothelium, Vascular,
pubmed-meshheading:18805782-Humans,
pubmed-meshheading:18805782-Intercellular Adhesion Molecule-1,
pubmed-meshheading:18805782-Monocytes,
pubmed-meshheading:18805782-Oxidative Stress,
pubmed-meshheading:18805782-Up-Regulation,
pubmed-meshheading:18805782-Vascular Cell Adhesion Molecule-1
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pubmed:year |
2009
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pubmed:articleTitle |
Endothelial CD81 is a marker of early human atherosclerotic plaques and facilitates monocyte adhesion.
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pubmed:affiliation |
Department of Medical Biochemistry, Academic Medical Centre, Amsterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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