|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0021083,
umls-concept:C0027428,
umls-concept:C0039194,
umls-concept:C0301869,
umls-concept:C0442805,
umls-concept:C0681850,
umls-concept:C1332714,
umls-concept:C1334114,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2607914,
umls-concept:C2697811
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2008-12-1
|
|
pubmed:abstractText |
We have previously shown that short-course treatment with Amb a 1-immunostimulatory phosphorothioate oligonucleotide conjugate (AIC) before the ragweed season modifies the response of the nasal mucosa to allergen challenge in ragweed-sensitive patients by increasing Th1 cytokines and decreasing both Th2 cytokines and eosinophilia after the ragweed season. The effect of AIC immunotherapy on CD4+CD25+ T cell expression in the nasal mucosa is unknown.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Allergens,
http://linkedlifedata.com/resource/pubmed/chemical/Amb a I protein, Ambrosia...,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD4,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Plant,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2 Receptor alpha Subunit,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphorothioate Oligonucleotides,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1323-8930
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
57
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
377-81
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:18797179-Allergens,
pubmed-meshheading:18797179-Ambrosia,
pubmed-meshheading:18797179-Antigens, CD4,
pubmed-meshheading:18797179-Antigens, Plant,
pubmed-meshheading:18797179-Biopsy,
pubmed-meshheading:18797179-Cell Count,
pubmed-meshheading:18797179-Desensitization, Immunologic,
pubmed-meshheading:18797179-Humans,
pubmed-meshheading:18797179-Immunohistochemistry,
pubmed-meshheading:18797179-Immunotherapy,
pubmed-meshheading:18797179-Interleukin-10,
pubmed-meshheading:18797179-Interleukin-2 Receptor alpha Subunit,
pubmed-meshheading:18797179-Lymphocyte Activation,
pubmed-meshheading:18797179-Nasal Mucosa,
pubmed-meshheading:18797179-Phosphorothioate Oligonucleotides,
pubmed-meshheading:18797179-Plant Proteins,
pubmed-meshheading:18797179-Pollen,
pubmed-meshheading:18797179-Rhinitis, Allergic, Seasonal,
pubmed-meshheading:18797179-T-Lymphocyte Subsets,
pubmed-meshheading:18797179-T-Lymphocytes, Regulatory,
pubmed-meshheading:18797179-Transforming Growth Factor beta
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy increases CD4+CD25+ T cells in the nasal mucosa of subjects with allergic rhinitis.
|
|
pubmed:affiliation |
Meakins-Christie Laboratories, McGill University, Quebec, Canada.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|
