Source:http://linkedlifedata.com/resource/pubmed/id/18773441
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2008-9-10
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pubmed:abstractText |
A 42-year-old man presented with severe abdominal pain, constipation, and hematuria. The patient had a history of seminoma treated by chemotherapy followed by bilateral orchiectomy and retroperitoneal lymph node dissection 16 years earlier. A computed tomography (CT) scan showed a 8.0 x 6.0 x 5.0 cm mass in the retrovesical space, encompassing the left side of his proximal bladder, the prostate, and the rectum. A urine cytologic specimen showed loosely cohesive cell clusters composed of highly atypical large cells and occasional large, single cells with macronucleoli present in a background of mainly lymphocytes and histiocytes was diagnosed as recurrent seminoma. Prostate biopsies showed extensively necrotic seminoma with accompanying granulomatous reaction. The tumor cells were immunoreactive for c-kit (CD117), placental-like alkaline phosphatase (PLAP), D2-40, and OCT4. To our knowledge, this is the second report on urine cytology of metastatic seminoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Octamer Transcription Factor-3,
http://linkedlifedata.com/resource/pubmed/chemical/POU5F1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-kit,
http://linkedlifedata.com/resource/pubmed/chemical/germ-cell AP isoenzyme
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1097-0339
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
734-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18773441-Adult,
pubmed-meshheading:18773441-Alkaline Phosphatase,
pubmed-meshheading:18773441-Biopsy,
pubmed-meshheading:18773441-Humans,
pubmed-meshheading:18773441-Isoenzymes,
pubmed-meshheading:18773441-Male,
pubmed-meshheading:18773441-Octamer Transcription Factor-3,
pubmed-meshheading:18773441-Prostate,
pubmed-meshheading:18773441-Prostatic Neoplasms,
pubmed-meshheading:18773441-Proto-Oncogene Proteins c-kit,
pubmed-meshheading:18773441-Seminoma,
pubmed-meshheading:18773441-Testicular Neoplasms,
pubmed-meshheading:18773441-Urinary Bladder Neoplasms,
pubmed-meshheading:18773441-Urine
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pubmed:year |
2008
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pubmed:articleTitle |
Cytologic diagnosis of metastatic seminoma to the prostate and urinary bladder: a case report.
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pubmed:affiliation |
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55455, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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