Linked Life Data

18766018

Source:http://linkedlifedata.com/resource/pubmed/id/18766018

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2008-9-3
pubmed:abstractText
We examined whether deficient prefrontal control over the semantic network exists in patients with schizophrenia. Fourteen patients with schizophrenia and 14 healthy controls performed a comparison task, judging semantic congruity according to an abstract category in an event-related functional MRI paradigm. In the control group, prefrontal-temporal networks consisting of the left inferior frontal gyrus and right inferior frontal sulcus converging at the left posterior superior temporal sulcus were identified as activated during semantic demand of incongruence. In the patients with schizophrenia, we observed a loss of the recruitment of the right inferior frontal sulcus and the prefrontal-temporal network. These findings indicate that cognitive modulation of semantic processing may be dysfunctional in patients with schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1473-558X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1391-5
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Prefrontal functional dissociation in the semantic network of patients with schizophrenia.
pubmed:affiliation
Departments of aPsychiatry bDiagnostic Radiology cInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Research Support, Non-U.S. Gov't