Linked Life Data

18766014

Source:http://linkedlifedata.com/resource/pubmed/id/18766014

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2008-9-3
pubmed:abstractText
We assessed the relationship between changes in corticosterone concentrations and hearing in mice exposed to noise during the light (inactive) and dark (active) phases. Serum corticosterone concentrations and hearing levels were measured before, and 1, 3, 5, 7, and 10 days after, noise exposure between 8:00-11:00 h and 15:00-18:00 h. Serum corticosterone concentrations were significantly lower at 8:00-11:00 h than at 15:00-18:00 h and were significantly lower before than after noise exposure. In addition, serum corticosterone concentrations were significantly lower at 11:00 h after noise exposure than at 18:00 h before noise exposure. Mice exposed to noise at 8:00-11:00 h showed significantly elevated threshold shifts after noise exposure than did mice exposed to noise at 15:00-18:00 h. Endogenous serum corticosterone concentration has a significant effect on hearing after noise exposure. Noise exposure during the inactive phase of the hypothalamic-pituitary-adrenal axis may be more harmful to the auditory system than noise exposure during the active phase of the hypothalamic-pituitary-adrenal axis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1473-558X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1373-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Circadian changes in serum corticosterone levels affect hearing in mice exposed to noise.
pubmed:affiliation
Department of Otolaryngology, Gangneung Asan Hospital, Gangneung, Gangwondo, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't