Linked Life Data

18754346

Source:http://linkedlifedata.com/resource/pubmed/id/18754346

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2008-8-29
pubmed:abstractText
Visible light-induced photocatalytic degradation of environmental pollutants with improved TiO2 has attracted much attention in pollution control and management. The degradation of nucleic acids is of great significance for biological contaminants such as viruses. In the presentwork, visible light-induced plasmid DNA damage catalyzed by a CdSe/ZnS-photosensitized nano-TiO2 film (QDs-TiO2 film) was investigated by atomic force microscopy (AFM) and agarose gel electrophoresis. Illuminated by visible light, the supercoiled pUC18 DNA could be damaged into nicked-circle and linear conformations by the QDs-TiO2 film. The percentage of different conformations of damaged DNA changed with illumination time. A statistical rule for calculating the quantity of supercoiled DNA has been established to evaluate the photocatalytic activity of the QDs-TiO2 film based on AFM results. Visible light-induced plasmid DNA damage catalyzed by the QDs-TiO2 film is characteristic of zero-order kinetics and the rate constant (k) is 3.5 x 10(-11) M x s(-1). Given an illumination time, the quantity of damaged supercoiled DNA catalyzed by the QDs-TiO2 film is constant.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0013-936X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5049-54
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Visible light-induced plasmid DNA damage catalyzed by a CdSe/ZnS-photosensitized nano-TiO2 film.
pubmed:affiliation
College of Chemistry and Molecular Sciences and State Key Laboratory of Virology, Wuhan University, Wuhan, 430072, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't