Source:http://linkedlifedata.com/resource/pubmed/id/18754321
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2008-8-29
|
| pubmed:abstractText |
We examined 73 children with respiratory infections for Chlamydophila (Chlamydia) pneumoniae and Mycoplasma pneumoniae using real-time PCR assay and serological tests. C. pneumoniae and M. pneumoniae infections were found in 11 (15.1%) and 6 (8.2%) cases, respectively. The sensitivities and specificities of real-time PCR versus definite diagnosis of acute infection were 63.6% and 100% for C. pneumoniae, and 100% and 100% for M. pneumoniae, respectively. C. pneumoniae PCR-negative results appeared to be due to poor growth of the organism. The sensitivity and specificity of ImmunoCard tests were 33.3% and 82.1%, respectively, indicating that the efficacy of rapid diagnosis was disputable. The present results suggest that real-time PCR is suitable for rapid diagnosis as a first screening test to determine first-line antibacterial agents to be used against these infectious diseases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0903-4641
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
116
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
477-83
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| pubmed:meshHeading |
pubmed-meshheading:18754321-Adolescent,
pubmed-meshheading:18754321-Agglutination Tests,
pubmed-meshheading:18754321-Antibodies, Bacterial,
pubmed-meshheading:18754321-Antigens, Bacterial,
pubmed-meshheading:18754321-Child,
pubmed-meshheading:18754321-Child, Preschool,
pubmed-meshheading:18754321-Chlamydophila Infections,
pubmed-meshheading:18754321-Chlamydophila pneumoniae,
pubmed-meshheading:18754321-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:18754321-Female,
pubmed-meshheading:18754321-Humans,
pubmed-meshheading:18754321-Infant,
pubmed-meshheading:18754321-Japan,
pubmed-meshheading:18754321-Male,
pubmed-meshheading:18754321-Mycoplasma pneumoniae,
pubmed-meshheading:18754321-Pneumonia, Mycoplasma,
pubmed-meshheading:18754321-Polymerase Chain Reaction,
pubmed-meshheading:18754321-Prospective Studies,
pubmed-meshheading:18754321-Respiratory Tract Infections,
pubmed-meshheading:18754321-Sensitivity and Specificity
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Analysis of children with Chlamydophila (Chlamydia) pneumoniae and Mycoplasma pneumoniae respiratoryinfections by real-time PCR assay and serological tests.
|
| pubmed:affiliation |
Department of Clinical Laboratory Science, Division of Health Sciences, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|