Linked Life Data

18753781

Source:http://linkedlifedata.com/resource/pubmed/id/18753781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-8-28
pubmed:abstractText
Interacting biological systems do not evolve independently, as exemplified many times at the cellular, organismal and ecosystem levels. Biological molecules interact tightly, and should therefore coevolve as well. Here we review the literature about molecular coevolution, between residues within RNAs or proteins, and between proteins. A panel of methodological and bioinformatic approaches have been developed to address this issue, yielding contrasting results: a strong coevolutionary signal is detected in RNA stems, whereas proteins show only moderate, uneasy to interpret departure from the independence hypothesis. The reasons for this discrepancy are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1660-9263
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-12
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Coevolution within and between genes.
pubmed:affiliation
Université Montpellier 2, Montpellier, France. galtier@univ-montp2.fr
pubmed:publicationType
Journal Article, Review