Source:http://linkedlifedata.com/resource/pubmed/id/18721209
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
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| pubmed:dateCreated |
2009-1-14
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| pubmed:abstractText |
The transcription factor nuclear factor-kappaB (NF-kappaB) is involved in inflammatory and immune responses through the induction of various cytokines and growth factors. Recently, the coordinated action of NF-kappaB and activator protein-1 was reported in osteopontin (OPN) expression. In the present study, we demonstrated that oxalate induces OPN expression by activating NF-kappaB in renal tubular cells. Furthermore, we investigated the inhibitory effect of N-acetyl-L-cysteine (NAC) on NF-kappaB activation in the human renal tubular cell line.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
1442-2042
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
924-8
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| pubmed:meshHeading |
pubmed-meshheading:18721209-Acetylcysteine,
pubmed-meshheading:18721209-Cells, Cultured,
pubmed-meshheading:18721209-Epithelial Cells,
pubmed-meshheading:18721209-Humans,
pubmed-meshheading:18721209-Kidney Tubules,
pubmed-meshheading:18721209-NF-kappa B,
pubmed-meshheading:18721209-Osteopontin,
pubmed-meshheading:18721209-Oxalates
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| pubmed:year |
2008
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| pubmed:articleTitle |
NF-kappaB activation in renal tubular epithelial cells by oxalate stimulation.
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| pubmed:affiliation |
Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Aichi, Japan. toza@med.nagoya-cu.ac.jp
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| pubmed:publicationType |
Journal Article
|