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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-11-10
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pubmed:abstractText |
Hepatitis C virus (HCV) is a leading cause of chronic hepatitis worldwide. Viral attachment and entry, representing the first steps of virus-host cell interactions, are major targets of adaptive host cell defenses. The mechanisms of antibody-mediated neutralization by host neutralizing responses in HCV infection are only poorly understood. Retroviral HCV pseudotypes (HCVpp) and recombinant cell culture-derived HCV (HCVcc) have been successfully used to study viral entry and antibody-mediated neutralization.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Anti-Idiotypic,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD81,
http://linkedlifedata.com/resource/pubmed/chemical/CD81 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis C Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Virus,
http://linkedlifedata.com/resource/pubmed/chemical/SCARB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class B,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Envelope Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/glycoprotein E2, Hepatitis C virus
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1528-0012
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pubmed:author |
pubmed-author:BartenschlagerRalfR,
pubmed-author:BarthHeidiH,
pubmed-author:BaumertThomas FTF,
pubmed-author:BlumHubert EHE,
pubmed-author:CarollaPatricP,
pubmed-author:CossetFrançois-LoicFL,
pubmed-author:DeplaErikE,
pubmed-author:DoffoëlMichelM,
pubmed-author:DreuxMarlèneM,
pubmed-author:HaberstrohAnitaA,
pubmed-author:KoutsoudakisGeorgeG,
pubmed-author:OwsiankaAniaA,
pubmed-author:PatelArvind HAH,
pubmed-author:SchnoberEva KEK,
pubmed-author:SchusterCatherineC,
pubmed-author:Stoll-KellerFrançoiseF,
pubmed-author:UnionAnnA,
pubmed-author:ZeiselMirjam BMB
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pubmed:issnType |
Electronic
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pubmed:volume |
135
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1719-1728.e1
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:18718838-Adult,
pubmed-meshheading:18718838-Aged,
pubmed-meshheading:18718838-Antibodies, Anti-Idiotypic,
pubmed-meshheading:18718838-Antibodies, Monoclonal,
pubmed-meshheading:18718838-Antigens, CD,
pubmed-meshheading:18718838-Antigens, CD81,
pubmed-meshheading:18718838-Cells, Cultured,
pubmed-meshheading:18718838-Hepacivirus,
pubmed-meshheading:18718838-Hepatitis C, Chronic,
pubmed-meshheading:18718838-Hepatitis C Antibodies,
pubmed-meshheading:18718838-Humans,
pubmed-meshheading:18718838-Immunoenzyme Techniques,
pubmed-meshheading:18718838-Immunoglobulin G,
pubmed-meshheading:18718838-Membrane Fusion,
pubmed-meshheading:18718838-Middle Aged,
pubmed-meshheading:18718838-Receptors, Virus,
pubmed-meshheading:18718838-Scavenger Receptors, Class B,
pubmed-meshheading:18718838-Viral Envelope Proteins
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pubmed:year |
2008
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pubmed:articleTitle |
Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.
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pubmed:affiliation |
Department of Medicine II, University of Freiburg, Freiburg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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