rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2008-8-18
|
pubmed:abstractText |
Prohibitin (PHB) was found to be overexpressed in breast cancer and thus is suggested as a biomarker in that disease. A few studies have investigated the PHB expression pattern in gastric cancer by two-dimensional gel electrophoresis. Uncertainties still existed on whether PHB expression could indicate the differentiation and apoptosis degree of gastric cancer and whether PHB protein as well as anti-PHB antibody could be a biomarker in the serum of the gastric cancer patient. In this study, the expression levels of PHB protein and mRNA of the tissues as well as PHB antigen and anti-PHB antibody in serum of patients with gastric cancer were systemically examined.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0944-1174
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
618-25
|
pubmed:meshHeading |
pubmed-meshheading:18709484-Adult,
pubmed-meshheading:18709484-Aged,
pubmed-meshheading:18709484-Blotting, Western,
pubmed-meshheading:18709484-Caenorhabditis elegans Proteins,
pubmed-meshheading:18709484-DNA, Neoplasm,
pubmed-meshheading:18709484-Diagnosis, Differential,
pubmed-meshheading:18709484-Female,
pubmed-meshheading:18709484-Gastric Mucosa,
pubmed-meshheading:18709484-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18709484-Humans,
pubmed-meshheading:18709484-Immunohistochemistry,
pubmed-meshheading:18709484-Male,
pubmed-meshheading:18709484-Middle Aged,
pubmed-meshheading:18709484-Polymerase Chain Reaction,
pubmed-meshheading:18709484-Repressor Proteins,
pubmed-meshheading:18709484-Retrospective Studies,
pubmed-meshheading:18709484-Stomach Neoplasms,
pubmed-meshheading:18709484-Tumor Markers, Biological,
pubmed-meshheading:18709484-Young Adult
|
pubmed:year |
2008
|
pubmed:articleTitle |
Prohibitin: a potential biomarker for tissue-based detection of gastric cancer.
|
pubmed:affiliation |
Central Laboratory, Putuo Hospital Affiliated Shanghai University of Traditional Chinese Medicine, Lanxi Road No. 164, Shanghai, 200062, China.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|