Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2008-10-6
pubmed:abstractText
Nanodiamonds that were prepared by high pressure/high temperature were functionalized with biomolecules for biological applications. Nanodiamonds (NDs, < or =35 nm) that were coated by silanization or with polyelectrolyte layers were grafted with a fluorescent thiolated peptide via a maleimido function; this led to an aqueous colloidal suspension that was stable for months. These substituted NDs were not cytotoxic for CHO cells. Their capacity to enter mammalian cells, and their localisation inside were ascertained after labelling the nucleus and actin, by examining the cells by confocal, reflected light and fluorescence microscopy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1439-7633
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2113-9
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells.
pubmed:affiliation
UPMC Université Paris 06, CNRS-UMR 7613, Synthèse, Structure et Fonction de Molécules Bioactives case courrier 182, 4 Place Jussieu, 75005 Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't