Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
2008-9-9
pubmed:abstractText
3-Methyl-1-butanol is a potential fuel additive or substitute. Previously this compound was identified in small quantities in yeast fermentation as one of the fusel alcohols. In this work, we engineered an Escherichia coli strain to produce 3-methyl-1-butanol from glucose via the host's amino acid biosynthetic pathways. Strain improvement with the removal of feedback inhibition and competing pathways increased the selectivity and productivity of 3-methyl-1-butanol. This work demonstrates the feasibility of production of 3-methyl-1-butanol as a biofuel and shows promise in using E. coli as a host for production.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-10802621, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-10829079, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-12778056, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-12937998, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-14586577, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-14982993, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-15950307, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-16041576, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-16217550, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-17158319, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-17337545, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-17933911, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-17942358, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-18172501, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-9092630, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-9341119, http://linkedlifedata.com/resource/pubmed/commentcorrection/18676713-9611822
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1098-5336
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5769-75
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Engineering of an Escherichia coli strain for the production of 3-methyl-1-butanol.
pubmed:affiliation
University of California, Department of Chemical and Biomolecular Engineering, 5531 Boelter Hall, Los Angeles, CA 90095, USAdu.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't