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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-9-12
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pubmed:abstractText |
Workers who have claimed an association between Fragile X [fra(x)] Syndrome and Hyperactivity and aggressive behavior have done so despite the lack of controlled studies using standard diagnostic criteria. Accordingly, we provided a controlled test of the hypothesis that individuals with the fra(x) Syndrome are more hyperactive and have more symptoms of aggression than other mentally retarded individuals. The test formed part of a study to assess autistic behavior in fra(x) individuals. A sample of fra(x) individuals was obtained from the register of a clinical genetics unit and individually matched for age, sex, and IQ with mentally retarded individuals selected from assessment centres. Forty-five pairs of fra(x) cases and control individuals were compared on criteria which reflected DSM-III concepts of hyperactivity and on criteria reflecting aggressive behavior. The comparison failed to find a higher prevalence of these symptoms in the fra(x) group. An analysis of the study's statistical power suggested that it is unlikely that the investigation failed to detect a large to medium difference between fra(x) individuals and control individuals in the symptoms investigated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0091-0627
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
253-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1865044-Adolescent,
pubmed-meshheading:1865044-Adult,
pubmed-meshheading:1865044-Aggression,
pubmed-meshheading:1865044-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:1865044-Autistic Disorder,
pubmed-meshheading:1865044-Child,
pubmed-meshheading:1865044-Child, Preschool,
pubmed-meshheading:1865044-Female,
pubmed-meshheading:1865044-Fragile X Syndrome,
pubmed-meshheading:1865044-Humans,
pubmed-meshheading:1865044-Karyotyping,
pubmed-meshheading:1865044-Male,
pubmed-meshheading:1865044-Personality Tests,
pubmed-meshheading:1865044-Psychometrics,
pubmed-meshheading:1865044-Risk Factors
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pubmed:year |
1991
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pubmed:articleTitle |
Hyperactivity and the fragile X syndrome.
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pubmed:affiliation |
Department of Psychiatry, University of Sydney, Australia.
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pubmed:publicationType |
Journal Article
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