| pubmed-article:18650095 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C1420119 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0061467 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0205464 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0243077 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0439611 | lld:lifeskim |
| pubmed-article:18650095 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:18650095 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:18650095 | pubmed:dateCreated | 2008-8-18 | lld:pubmed |
| pubmed-article:18650095 | pubmed:abstractText | A series of beta-benzylaspartate derivatives were prepared from N-trityl-L-aspartate dimethyl ester and evaluated as inhibitors of neuronal glutamate transporter EAAT3. The result of the structure-activity studies suggests that the position occupied by the aromatic ring of beta-benzylaspartate within the binding site of EAAT3 may be different from that occupied by comparable groups in previously identified inhibitors, such as L-threo-benzyloxy aspartate (TBOA). Further, halogen substitutions at the 3-position of the aromatic ring of beta-benzylaspartate can increase the potency with which the analogues inhibit EAAT3. | lld:pubmed |
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| pubmed-article:18650095 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18650095 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18650095 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:18650095 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18650095 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:18650095 | pubmed:issn | 1464-3391 | lld:pubmed |
| pubmed-article:18650095 | pubmed:author | pubmed-author:EsslingerC... | lld:pubmed |
| pubmed-article:18650095 | pubmed:author | pubmed-author:BridgesRichar... | lld:pubmed |
| pubmed-article:18650095 | pubmed:author | pubmed-author:RhoderickJose... | lld:pubmed |
| pubmed-article:18650095 | pubmed:author | pubmed-author:MavencampTerr... | lld:pubmed |
| pubmed-article:18650095 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18650095 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:18650095 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:18650095 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18650095 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18650095 | pubmed:pagination | 7740-8 | lld:pubmed |
| pubmed-article:18650095 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:meshHeading | pubmed-meshheading:18650095... | lld:pubmed |
| pubmed-article:18650095 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18650095 | pubmed:articleTitle | Synthesis and preliminary pharmacological evaluation of novel derivatives of L-beta-threo-benzylaspartate as inhibitors of the neuronal glutamate transporter EAAT3. | lld:pubmed |
| pubmed-article:18650095 | pubmed:affiliation | NIH-COBRE Center for Structural and Functional Neuroscience, Department of Biomedical & Pharmaceutical Sciences, The University of Montana, Missoula, MT 59812, USA. | lld:pubmed |
| pubmed-article:18650095 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18650095 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18650095 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18650095 | lld:pubmed |
