Linked Life Data

18642601

Source:http://linkedlifedata.com/resource/pubmed/id/18642601

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-7-22
pubmed:abstractText
The comet assay, also known as the single-cell gel electrophoresis assay, is a method of detecting DNA damage in virtually any nucleated cell. The comet assay has significant advantages over other genotoxicity tests, but it is very sensitive to subtle changes that can yield appreciable variability in results. The purpose of our chapter is to present background information and detailed standard operating procedures for the use of the alkaline comet assay in environmental genotoxicity assessment. We address pitfalls and concerns associated with conducting the comet assay, and briefly discuss modifications of the general alkaline procedure that can be used to address different issues relevant to environmental toxicology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1064-3745
pubmed:author
pubmed:issnType
Print
pubmed:volume
410
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-83
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Use of the comet assay in environmental toxicology.
pubmed:affiliation
Jacques Whitford, Ottawa, Ontario, Canada.
pubmed:publicationType
Journal Article