Source:http://linkedlifedata.com/resource/pubmed/id/18618396
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2008-7-17
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| pubmed:abstractText |
An effective synthetic route of l-muscone (1) by asymmetric methylation, followed by enolate-trapping to generate enol esters as intermediates, was described. Interestingly, the enol esters can be used as substrates for enzymatic optical resolution to improve optical purity. Additionally, several excellent new chiral ligands were discovered for asymmetric methylation of (E)-cyclopentadec-2-enone to produce l-muscone with high optical purity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
1612-1880
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1023-33
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| pubmed:meshHeading | |
| pubmed:year |
2008
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| pubmed:articleTitle |
Synthesis of l-muscone by asymmetric methylation via enol esters.
|
| pubmed:affiliation |
Takasago International Corporation, Central Research Laboratory, 1-4-11 Nishi-yawata, Hiratsuka city, Kanagawa 254-0073, Japan. hiroyuki_matsuda@takasago.com
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| pubmed:publicationType |
Journal Article
|