pubmed-article:18601967 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:18601967 | lifeskim:mentions | umls-concept:C0019169 | lld:lifeskim |
pubmed-article:18601967 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
pubmed-article:18601967 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
pubmed-article:18601967 | lifeskim:mentions | umls-concept:C1704410 | lld:lifeskim |
pubmed-article:18601967 | lifeskim:mentions | umls-concept:C2368628 | lld:lifeskim |
pubmed-article:18601967 | pubmed:issue | 35 | lld:pubmed |
pubmed-article:18601967 | pubmed:dateCreated | 2008-8-6 | lld:pubmed |
pubmed-article:18601967 | pubmed:abstractText | Transgenic tobacco plants expressing a HIV-1 polyepitope associated with hepatitis B (HBV) virus-like particles (VLPs) were previously described. It is demonstrated here that oral administration of these transgenic plants to humanized HSB mice to boost DNA-priming can elicit anti-HIV-1 specific CD8+ T cell activation detectable in mesenteric lymph nodes. Nevertheless, a significant regulatory T cell activation was induced in vivo by the vaccination protocols. The balance between tolerance and immunogenicity remains the main concern in the proof of concept of plant-based vaccine. | lld:pubmed |
pubmed-article:18601967 | pubmed:language | eng | lld:pubmed |
pubmed-article:18601967 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18601967 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:18601967 | pubmed:month | Aug | lld:pubmed |
pubmed-article:18601967 | pubmed:issn | 0264-410X | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:Langlade-Demo... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:Wain-HobsonSi... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:SalaFrancesco... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:CelliSusannaS | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:GrecoRaffaell... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:GuetardDenise... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:SalaMonicaM | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:Cervantes... | lld:pubmed |
pubmed-article:18601967 | pubmed:author | pubmed-author:KostrzakAnnaA | lld:pubmed |
pubmed-article:18601967 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:18601967 | pubmed:day | 18 | lld:pubmed |
pubmed-article:18601967 | pubmed:volume | 26 | lld:pubmed |
pubmed-article:18601967 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:18601967 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:18601967 | pubmed:pagination | 4477-85 | lld:pubmed |
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pubmed-article:18601967 | pubmed:year | 2008 | lld:pubmed |
pubmed-article:18601967 | pubmed:articleTitle | Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration. | lld:pubmed |
pubmed-article:18601967 | pubmed:affiliation | Department of Virology, Unité de Rétrovirologie Moléculaire, CNRS URA 3015, Institut Pasteur, 28 rue du Dr Roux, 75015 Paris, France. | lld:pubmed |
pubmed-article:18601967 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:18601967 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18601967 | lld:pubmed |