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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-7-7
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pubmed:abstractText |
Real-time reverse transcription polymerase chain reaction (qRT-PCR) was used to evaluate gene expression of adenosine kinase, a key enzyme in adenosine metabolism, in human intestinal biopsy specimens of 10 colorectal cancer patients. Quantitative mRNA expression levels were normalized against the reference gene beta-actin. The results showed that adenosine kinase gene expression was significantly higher in cancer than in normal-appearing tissue, in line with our previous measurements of adenosine kinase enzyme activities in colorectal tumor samples.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1532-2335
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
750-4
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pubmed:meshHeading |
pubmed-meshheading:18600536-Adenosine,
pubmed-meshheading:18600536-Adenosine Kinase,
pubmed-meshheading:18600536-Aged,
pubmed-meshheading:18600536-Aged, 80 and over,
pubmed-meshheading:18600536-Biopsy,
pubmed-meshheading:18600536-Cell Proliferation,
pubmed-meshheading:18600536-Colorectal Neoplasms,
pubmed-meshheading:18600536-Female,
pubmed-meshheading:18600536-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18600536-Humans,
pubmed-meshheading:18600536-Intestines,
pubmed-meshheading:18600536-Male,
pubmed-meshheading:18600536-Middle Aged,
pubmed-meshheading:18600536-Mucous Membrane,
pubmed-meshheading:18600536-RNA, Messenger
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pubmed:year |
2008
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pubmed:articleTitle |
Adenosine kinase gene expression in human colorectal cancer.
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pubmed:affiliation |
Dipartimento di Medicina Interna, Sc. Endocrino-Metaboliche e Biochimica, Università di Siena, Italy.
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pubmed:publicationType |
Journal Article
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