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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-7-28
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pubmed:abstractText |
Urothelial carcinomas originate from the epithelial cells of the inner lining of the bladder and may appear as single or as multiple synchronous tumors. Patients with urothelial carcinomas frequently show recurrences after treatment making follow-up necessary. The leading hypothesis explaining the origin of meta- and synchronous tumors assumes a monoclonal origin. However, the genetic relationship among consecutive tumors has been shown to be complex in as much as the genetic evolution does not adhere to the chronological appearance of the metachronous tumors. Consequently, genetically less evolved tumors may appear chronologically later than genetically related but more evolved tumors.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-10022124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-10197433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-10487605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-10534167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-10719370,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-11115841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-11196186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-11395371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-11719456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-12186655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-12209580,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-1445507,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-15161696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-15173019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-16083510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-16110317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-16426913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-16532037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-16574430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-17123702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-18237450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-9160886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18590527-9426409
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
pubmed-author:AitsSonjaS,
pubmed-author:AnderssonAnnaA,
pubmed-author:BorgAkeA,
pubmed-author:ChebilGunillaG,
pubmed-author:FioretosThoasT,
pubmed-author:GudjonssonSigurdurS,
pubmed-author:HöglundMattiasM,
pubmed-author:JeeKowan JaKJ,
pubmed-author:KnuutilaSakariS,
pubmed-author:LiedbergFredrikF,
pubmed-author:LindgrenDavidD,
pubmed-author:MånssonWikingW
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
183
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18590527-Carcinoma,
pubmed-meshheading:18590527-Cell Transformation, Neoplastic,
pubmed-meshheading:18590527-DNA Mutational Analysis,
pubmed-meshheading:18590527-Female,
pubmed-meshheading:18590527-Gene Expression Profiling,
pubmed-meshheading:18590527-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18590527-Humans,
pubmed-meshheading:18590527-Male,
pubmed-meshheading:18590527-Neoplasm Recurrence, Local,
pubmed-meshheading:18590527-Neoplasm Staging,
pubmed-meshheading:18590527-Neoplasms, Multiple Primary,
pubmed-meshheading:18590527-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:18590527-Point Mutation,
pubmed-meshheading:18590527-Receptor, Fibroblast Growth Factor, Type 3,
pubmed-meshheading:18590527-Tumor Suppressor Protein p53,
pubmed-meshheading:18590527-Urinary Bladder Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
Recurrent and multiple bladder tumors show conserved expression profiles.
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pubmed:affiliation |
Department of Clinical Genetics, Lund University Hospital, Lund, Sweden. david.lindgren@med.lu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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