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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2008-6-26
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pubmed:abstractText |
Selection of specific human leukocyte antigen (HLA)-restricted cytotoxic T-lymphocyte (CTL) escape mutations in key Gag epitopes has been associated with loss of HIV immune control on an individual basis. Here we undertake a population-based identification of HLA-associated polymorphisms in Gag and investigate their relationship with plasma viral load.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1473-5571
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pubmed:author |
pubmed-author:BranderChristianC,
pubmed-author:BrummeChanson JCJ,
pubmed-author:BrummeZabrina LZL,
pubmed-author:CarlsonJonathan MJM,
pubmed-author:ChanDennisonD,
pubmed-author:FrahmNicoleN,
pubmed-author:HarriganP RichardPR,
pubmed-author:HeckermanDavidD,
pubmed-author:KadieCarlC,
pubmed-author:SzetoSharonS,
pubmed-author:TaoIrisI,
pubmed-author:WalkerBruceB
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1277-86
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pubmed:meshHeading |
pubmed-meshheading:18580606-Amino Acid Sequence,
pubmed-meshheading:18580606-CD4 Lymphocyte Count,
pubmed-meshheading:18580606-Chronic Disease,
pubmed-meshheading:18580606-Cross-Sectional Studies,
pubmed-meshheading:18580606-Genes, MHC Class I,
pubmed-meshheading:18580606-HIV Infections,
pubmed-meshheading:18580606-HIV-1,
pubmed-meshheading:18580606-Humans,
pubmed-meshheading:18580606-Molecular Sequence Data,
pubmed-meshheading:18580606-Polymorphism, Genetic,
pubmed-meshheading:18580606-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:18580606-Viral Load,
pubmed-meshheading:18580606-gag Gene Products, Human Immunodeficiency Virus
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pubmed:year |
2008
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pubmed:articleTitle |
Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection.
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pubmed:affiliation |
Partners AIDS Research Center, Massachusetts General Hospital, Boston, Harvard Medical School, Massachusetts 02129, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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