|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2008-7-15
|
|
pubmed:abstractText |
Activated adhesive signaling is a hallmark of fibroblasts isolated from the scars of scleroderma (systemic sclerosis [SSc]) lesions. Rac1 plays a key role in adhesive signaling. The aim of the present study was to examine the role of Rac1 in bleomycin-induced scleroderma, using mice with a fibroblast-specific deletion of Rac1.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
58
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2189-95
|
|
pubmed:meshHeading |
pubmed-meshheading:18576327-Animals,
pubmed-meshheading:18576327-Antibiotics, Antineoplastic,
pubmed-meshheading:18576327-Bleomycin,
pubmed-meshheading:18576327-Disease Models, Animal,
pubmed-meshheading:18576327-Fibroblasts,
pubmed-meshheading:18576327-Gene Expression,
pubmed-meshheading:18576327-Mice,
pubmed-meshheading:18576327-Mice, Inbred C57BL,
pubmed-meshheading:18576327-Mice, Knockout,
pubmed-meshheading:18576327-Neuropeptides,
pubmed-meshheading:18576327-Scleroderma, Localized,
pubmed-meshheading:18576327-rac GTP-Binding Proteins
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Role of Rac1 in a bleomycin-induced scleroderma model using fibroblast-specific Rac1-knockout mice.
|
|
pubmed:affiliation |
University of Western Ontario, London, Ontario, Canada.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
