rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2008-6-24
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pubmed:abstractText |
High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic cells and by activated immune cells. HMGB1 signals via members of the toll-like receptor family and the receptor for advanced glycation end products (RAGE). Although HMGB1 has been implicated in ischemia/reperfusion (I/R) injury of the liver and lung, its role in I/R injury of the heart remains unclear.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:AndrassyMartinM,
pubmed-author:AutschbachFrankF,
pubmed-author:BeaFlorianF,
pubmed-author:BianchiMarco EME,
pubmed-author:BierhausAngelikaA,
pubmed-author:BussSebastianS,
pubmed-author:EichbergerSebastian NSN,
pubmed-author:FunkeBenjaminB,
pubmed-author:HardtStefan ESE,
pubmed-author:HumpertPer MPM,
pubmed-author:IgweJohn CJC,
pubmed-author:KatusHugo AHA,
pubmed-author:KayaZiyaZ,
pubmed-author:LukicIvan KIK,
pubmed-author:MairbäurlHeimoH,
pubmed-author:NawrothPeter PPP,
pubmed-author:PlegerSven TST,
pubmed-author:RemppisAndrewA,
pubmed-author:VolzHans CHC
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3216-26
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pubmed:meshHeading |
pubmed-meshheading:18574060-Animals,
pubmed-meshheading:18574060-Cells, Cultured,
pubmed-meshheading:18574060-Echocardiography,
pubmed-meshheading:18574060-HMGB1 Protein,
pubmed-meshheading:18574060-Immunohistochemistry,
pubmed-meshheading:18574060-Macrophages,
pubmed-meshheading:18574060-Mice,
pubmed-meshheading:18574060-Mice, Inbred C57BL,
pubmed-meshheading:18574060-Mice, Knockout,
pubmed-meshheading:18574060-Myocardial Ischemia,
pubmed-meshheading:18574060-Protein Binding,
pubmed-meshheading:18574060-Receptors, Immunologic,
pubmed-meshheading:18574060-Recombinant Proteins,
pubmed-meshheading:18574060-Reperfusion Injury,
pubmed-meshheading:18574060-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18574060-Signal Transduction,
pubmed-meshheading:18574060-Up-Regulation
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pubmed:year |
2008
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pubmed:articleTitle |
High-mobility group box-1 in ischemia-reperfusion injury of the heart.
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pubmed:affiliation |
Department of Medicine III, University of Heidelberg, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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