Linked Life Data

18566772

Source:http://linkedlifedata.com/resource/pubmed/id/18566772

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-6-20
pubmed:abstractText
Most phylogenetic methods are model-based and depend on Markov models designed to approximate the evolutionary rates between nucleotides or amino acids. When Markov models are selected for analysis of alignments of these characters, it is assumed that they are close approximations of the evolutionary processes that gave rise to the data. A variety of methods have been developed for estimating the fit of Markov models, and some of these methods are now frequently used for the selection of Markov models. In a growing number of cases, however, it appears that the investigators have used the model-selection methods without acknowledging their inherent shortcomings. This chapter reviews the issue of model selection and model evaluation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1064-3745
pubmed:author
pubmed:issnType
Print
pubmed:volume
452
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
331-64
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Phylogenetic model evaluation.
pubmed:affiliation
School of Mathematics and Statistics, Sydney Bioinformatics and Centre for Mathematical Biology, University of Sydney, Sydney, New South Wales, Australia.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't