Source:http://linkedlifedata.com/resource/pubmed/id/18555318
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-6-16
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pubmed:abstractText |
Immobilized heparins were prepared by six different methods, and these were utilized for affinity purification of human antithrombin III (AT-III). Affinity support capacities (mg AT-III/g support) were strongly influenced by immobilized active heparin concentrations. In the temperature range 5-37 degrees C, colder temperatures favored affinity adsorption of AT-III as well as nonspecific interactions of all proteins. For representative human-plasma-derived feed solutions the selectivity for AT-III on the affinity support was dependent on relative concentrations of non-AT-III proteins as well as the specific mode of adsorption and elution (batch/continuous).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3592
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
217-22
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pubmed:year |
1986
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pubmed:articleTitle |
Application of immobilized heparins for isolation of human antithrombin III.
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pubmed:affiliation |
Biological Research and Development, Cutter Laboratories, Fourth and Parker Streets, Berkeley, California 94710, USA.
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pubmed:publicationType |
Journal Article
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