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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-12-9
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pubmed:abstractText |
In a phase-III trial it was recently shown that an adjuvant renal cell carcinoma (RCC) vaccine (Reniale) reduces the risk of tumour progression following nephrectomy. This clinical trial focused on efficacy and did not investigate end-points relating to mode-of-action of the vaccine. In a murine model we investigated mode-of-action, efficacy, and safety of a homologous RENCA cell-based vaccine.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1873-7560
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-31
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pubmed:meshHeading |
pubmed-meshheading:18550267-Adaptive Immunity,
pubmed-meshheading:18550267-Adoptive Transfer,
pubmed-meshheading:18550267-Animals,
pubmed-meshheading:18550267-Cancer Vaccines,
pubmed-meshheading:18550267-Carcinoma, Renal Cell,
pubmed-meshheading:18550267-Cell Line, Tumor,
pubmed-meshheading:18550267-Combined Modality Therapy,
pubmed-meshheading:18550267-Disease Models, Animal,
pubmed-meshheading:18550267-Female,
pubmed-meshheading:18550267-Kidney Neoplasms,
pubmed-meshheading:18550267-Killer Cells, Natural,
pubmed-meshheading:18550267-Lung Neoplasms,
pubmed-meshheading:18550267-Lymphocyte Count,
pubmed-meshheading:18550267-Mice,
pubmed-meshheading:18550267-Mice, Inbred BALB C,
pubmed-meshheading:18550267-Nephrectomy,
pubmed-meshheading:18550267-Spleen,
pubmed-meshheading:18550267-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:18550267-Tumor Burden
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pubmed:year |
2009
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pubmed:articleTitle |
Mode-of-action, efficacy, and safety of a homologous multi-epitope vaccine in a murine model for adjuvant treatment of renal cell carcinoma.
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pubmed:affiliation |
Department of Urology, University of Lübeck Medical School, Lübeck, Germany. doehn@medinf.mu-luebeck.de
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pubmed:publicationType |
Journal Article
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