Source:http://linkedlifedata.com/resource/pubmed/id/18545554
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2008-6-11
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pubmed:abstractText |
An alternative optical coherence tomography (OCT) to clinical ophthalmic 830 nm spectral-domain OCTs (SD-OCT) is demonstrated. An axial resolution of 7.4 microm, ranging depth of 4.2 mm in tissue, sensitivity of 98.5 dB, and detection speed of 38,300 axial scans/s have been achieved. These are comparable or superior to those of recently commercially available ophthalmic 830 nm SD-OCTs in clinics. In addition, fast volumetric imaging for the in vivo human posterior eye with high-contrast of the choroid is achieved. A broadband 1.04 microm light source enables the high-contrast and high resolution imaging of the retina and choroid. The ranging depth is extended by applying a full-range imaging method with an electro-optic modulator (BM-scan method). A prototype high-speed InGaAs line scan camera with 1024 pixels is used. A newly reported sensitivity improvement property of the BM-scan method demonstrates a sensitivity enhancement of 5.1 dB. We also introduce a newly developed resampling calibration method of spectrum that is independent of the intrinsic dispersion mismatch of the interferometer. The three-dimensional structure of the in vivo human optic nerve head with a very deep cupping is successfully visualized.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1094-4087
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
9
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8406-20
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pubmed:meshHeading |
pubmed-meshheading:18545554-Choroid,
pubmed-meshheading:18545554-Humans,
pubmed-meshheading:18545554-Image Enhancement,
pubmed-meshheading:18545554-Imaging, Three-Dimensional,
pubmed-meshheading:18545554-Pilot Projects,
pubmed-meshheading:18545554-Reproducibility of Results,
pubmed-meshheading:18545554-Retina,
pubmed-meshheading:18545554-Retinoscopes,
pubmed-meshheading:18545554-Sensitivity and Specificity,
pubmed-meshheading:18545554-Tomography, Optical Coherence
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pubmed:year |
2008
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pubmed:articleTitle |
Full-range, high-speed, high-resolution 1 microm spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye.
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pubmed:affiliation |
Computational Optics Group in the University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 3058573, Japan. makita@optlab2.bk.tsukuba.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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