Source:http://linkedlifedata.com/resource/pubmed/id/18509343
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2008-10-16
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pubmed:abstractText |
Dependence of the ambulatory arterial stiffness index (AASI) on data scattering interferes with its potential clinical relevance. We assessed the correlates and all-cause mortality associations of a modified AASI (s-AASI). AASI was derived from the 24-h diastolic vs. systolic blood pressure linear regression line, whereas s-AASI was derived by symmetric regression (bisecting the line of diastolic vs systolic and systolic vs. diastolic). Of 2918 patients 55% were women; age was 56 +/- 16 years and body mass index was 27.3 +/- 4.5 kg/m(2). Average 24-h ambulatory blood pressure was 138 +/- 16/78 +/- 10 mm Hg. Applying the modified method for calculating AASI yielded a different measure: the negative correlation between AASI and blood pressure dipping (r = -0.304, P < 0.0001) was abolished (r = +0.223, P < 0.0001), s-AASI was more dependent on age (r = 0.266 vs. r = 0.089 for AASI), and prediction of all-cause mortality was enhanced; hazard ratio (95% confidence intervals) 1.17 (1.00-1.36) per 1 s.d. increase in s-AASI in the fully adjusted model as compared with 1.15 (0.97-1.36) for AASI.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0950-9240
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
761-6
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pubmed:meshHeading |
pubmed-meshheading:18509343-Blood Pressure,
pubmed-meshheading:18509343-Blood Pressure Monitoring, Ambulatory,
pubmed-meshheading:18509343-Cause of Death,
pubmed-meshheading:18509343-Female,
pubmed-meshheading:18509343-Follow-Up Studies,
pubmed-meshheading:18509343-Humans,
pubmed-meshheading:18509343-Hypertension,
pubmed-meshheading:18509343-Israel,
pubmed-meshheading:18509343-Male,
pubmed-meshheading:18509343-Middle Aged,
pubmed-meshheading:18509343-Prognosis,
pubmed-meshheading:18509343-Proportional Hazards Models,
pubmed-meshheading:18509343-Retrospective Studies,
pubmed-meshheading:18509343-Risk Factors,
pubmed-meshheading:18509343-Survival Rate,
pubmed-meshheading:18509343-Vascular Resistance
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pubmed:year |
2008
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pubmed:articleTitle |
A modified ambulatory arterial stiffness index is independently associated with all-cause mortality.
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pubmed:affiliation |
Nephrology and Hypertension Services, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. iddobe@ekmd.huji.ac.il
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pubmed:publicationType |
Journal Article,
Comparative Study
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