Linked Life Data

18499443

Source:http://linkedlifedata.com/resource/pubmed/id/18499443

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-9-1
pubmed:abstractText
The presence of lymph node (LN) metastases has a major impact on the prognosis of women with endometrial cancer and compromises recurrence-free time. LN assessment has become the standard of care in the surgical staging of patients and plays a crucial role in decision making. Sentinel lymph node (SLN) detection improves the accuracy of lymphatic drainage mapping compared to pelvic node dissection used alone. Serial sectioning of SLNs followed by immunohistochemical examination with conventional histology improves accuracy of micrometastatic identification. In this review, we found a high incidence of micrometastases in endometrial cancer, reaching 25% depending on the stage and the techniques used for the node examination. Current data are insufficient to evaluate the prognostic impact of the presence of micrometastases, but it seems that more accurate detection of lymphatic spread will allow better stratification of intermediate risk patients. Ultimately, this will assist in tailoring adjuvant treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0960-7404
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-45
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Sentinel lymph node evaluation in endometrial cancer and the importance of micrometastases.
pubmed:affiliation
Department of Gynaecology and Obstetrics, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Paris, France.
pubmed:publicationType
Journal Article, Review