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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6315
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pubmed:dateCreated |
1991-4-19
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pubmed:abstractText |
Autoreactive T lymphocytes are clonally deleted during maturation in the thymus. Deletion of T cells expressing particular receptor V beta elements is controlled by poorly defined autosomal dominant genes. A gene has now been identified by expression of transgenes in mice which causes deletion of V beta 14+ T cells. The gene lies in the open reading frame of the long terminal repeat of the mouse mammary tumour virus.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
350
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
207-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1848685-Amino Acid Sequence,
pubmed-meshheading:1848685-Animals,
pubmed-meshheading:1848685-Chromosome Deletion,
pubmed-meshheading:1848685-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:1848685-Female,
pubmed-meshheading:1848685-Genes, Viral,
pubmed-meshheading:1848685-Mammary Tumor Virus, Mouse,
pubmed-meshheading:1848685-Mice,
pubmed-meshheading:1848685-Mice, Transgenic,
pubmed-meshheading:1848685-Molecular Sequence Data,
pubmed-meshheading:1848685-Open Reading Frames,
pubmed-meshheading:1848685-Phenotype,
pubmed-meshheading:1848685-Proviruses,
pubmed-meshheading:1848685-Receptors, Antigen, T-Cell,
pubmed-meshheading:1848685-T-Lymphocytes
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pubmed:year |
1991
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pubmed:articleTitle |
Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus.
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pubmed:affiliation |
Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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