Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2008-6-30
pubmed:abstractText
Non-adherence to epilepsy medications can interfere with treatment and may adversely affect clinical outcomes, although few studies have examined this relationship. This study assessed barriers and drivers to adherence, its impact on quality of life, and the importance of the patient-physician relationship to adherence. Two cross-sectional online surveys were conducted among 408 adult patients with epilepsy and 175 neurologists who treat epilepsy patients. Twenty-nine percent of patients self-reported being non-adherent to antiepileptic medications in the prior month. Non-adherence was found to be associated with reduced seizure control, lowered quality of life, decreased productivity, seizure-related job loss, and seizure-related motor vehicle accidents. Patient-oriented epilepsy treatment programs and clear communication strategies to promote self-management and patients' understanding of epilepsy are essential to maximizing treatment and quality of life outcomes while also minimizing economic costs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1525-5069
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-22
pubmed:meshHeading
pubmed-meshheading:18472303-Accidents, Traffic, pubmed-meshheading:18472303-Activities of Daily Living, pubmed-meshheading:18472303-Adolescent, pubmed-meshheading:18472303-Adult, pubmed-meshheading:18472303-Anticonvulsants, pubmed-meshheading:18472303-Cross-Sectional Studies, pubmed-meshheading:18472303-Epilepsy, pubmed-meshheading:18472303-Female, pubmed-meshheading:18472303-Health Surveys, pubmed-meshheading:18472303-Humans, pubmed-meshheading:18472303-Male, pubmed-meshheading:18472303-Middle Aged, pubmed-meshheading:18472303-Motivation, pubmed-meshheading:18472303-Multivariate Analysis, pubmed-meshheading:18472303-Patient Education as Topic, pubmed-meshheading:18472303-Physician-Patient Relations, pubmed-meshheading:18472303-Quality of Life, pubmed-meshheading:18472303-Self Care, pubmed-meshheading:18472303-Socioeconomic Factors, pubmed-meshheading:18472303-Treatment Refusal, pubmed-meshheading:18472303-Unemployment, pubmed-meshheading:18472303-United States
pubmed:year
2008
pubmed:articleTitle
Association of non-adherence to antiepileptic drugs and seizures, quality of life, and productivity: survey of patients with epilepsy and physicians.
pubmed:affiliation
University of Tennessee Health Science Center, Memphis, TN 38103, USA. chovinga@utmem.edu
pubmed:publicationType
Journal Article